Analysis of the restriction to the growth of nonegg-adapted human influenza virus in eggs.

doi:10.1006/viro.1993.1522

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Article

Analysis of the restriction to the growth of nonegg-adapted human influenza virus in eggs.

Virology - 1 Oct 1993

Williams S P, Robertson J S

Abstract excerpt

When nonegg-adapted human influenza virus, i.e., either the natural virus present in a clinical specimen or an isolate propagated exclusively in tissue culture cells, is first passaged in the allantoic cavity of embryonated hens' eggs, variants which have amino acid substitutions around the recep...

Topics

Adaptation, Biological
Allantois
Animal Population Groups
Animals
Biological Transport
Cells, Cultured
Chick Embryo
Genetic Variation
Hot Temperature
Influenza A virus
Kinetics
Neuraminidase
Receptors, Virus

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