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Article

Effects of host-dependent glycosylation of hemagglutinin on receptor-binding properties on H1N1 human influenza A virus grown in MDCK cells and in embryonated eggs.

Virology - 1 Aug 1998

Gambaryan A S, Marinina V P, Tuzikov A B, Bovin N V, Rudneva I A, Sinitsyn B V, Shilov A A, Matrosovich M N

Abstract excerpt

There is growing evidence that the receptor-binding characteristics of influenza viruses are affected by the host-dependent glycosylation of viral hemagglutinin (HA). To better understand these effects, we propagated two variants of the human influenza virus USSR/90/77 (which differed by the mutation Asn131 reversible Asp131 in the glycosylation sequon of their HA) in either embryonated chicken eggs or MDCK cell....

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PMID: 9705910
DOI: 10.1006/viro.1998.9224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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