Article
An overview of host cell selection.
Developments in biological standardization - 1 Jan 1999
Robertson J S
Abstract excerpt
A virus with a new phenotype can arise from an apparently homogeneous population after a single passage by the application of a strong selection pressure. With less pressure, a variant population may arise gradually during repeated passage of the virus. Strong host selection has been observed when naturally occurring influenza virus is grown in embryonated hens' eggs whereas the natural virus grows apparently...
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