Article
P53 mutations in human cancer.
Leukemia - 1 Aug 1993
Miller C, Koeffler H P
Abstract excerpt
A 53,000 dalton protein called p53, was noted to be mutated in human cancer in 1987. Further studies have shown that p53 is a tumor suppressor gene which may be one of the most frequently altered genes in cancer of all types. These alterations include interactions with viral antigens, coding muta...
Topics
- Codon
- Exons
- Female
- Gene Rearrangement
- Genes, p53
- Genital Neoplasms, Female
- Humans
- Leukemia
- Lymphoma
- Male
- Mutation
- Neoplasms
- Osteosarcoma