Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model.

doi:10.1128/iai.61.9.3811-3817.1993

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Article

Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model.

Infection and immunity - 1 Sept 1993

Yamashita Y, Bowen W H, Burne R A, Kuramitsu H K

Abstract excerpt

The role of each of the Streptococcus mutans gtf genes coding for glucan synthesis in cariogenesis was evaluated by using strain UA130 in the specific-pathogen-free (SPF) rat model system. Mutants defective in either or both of the genes required for insoluble glucan synthesis, the gtfB and gtfC...

Topics

Animals
Dental Caries
Genes, Bacterial
Glucosyltransferases
Mutation
Polysaccharides
Rats
Rats, Sprague-Dawley
Specific Pathogen-Free Organisms
Streptococcus mutans

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