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Article

Inactivation ofStreptococcus mutansgeneslytSTanddltADimpairs its pathogenicityin vivo

1 Jan 2019

Abstract excerpt

Background: Streptococcus mutans orchestrates the development of a biofilm that causes dental caries in the presence of dietary sucrose, and, in the bloodstream, S. mutans can cause systemic infections. The development of a cariogenic biofilm is dependent on the formation of an extracellular matrix rich in exopolysaccharides, which contains extracellular DNA (eDNA) and lipoteichoic acids (LTAs). While the...

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PMID: 31143407
DOI: 10.1080/20002297.2019.1607505

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