Article
<i>Streptococcus mutans:</i> Fructose Transport, Xylitol Resistance, and Virulence
1 Apr 2006
Abstract excerpt
Streptococcus mutans, the primary etiological agent of human dental caries, possesses at least two fructose phosphotransferase systems (PTSs), encoded by fruI and fruCD. fruI is also responsible for xylitol transport. We hypothesized that fructose and xylitol transport systems do not affect virulence. Thus, colonization and cariogenicity of fruI(-) and fruCD(-) single and double mutants, their WT (UA159), and...
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