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Article

The role of glucan-binding proteins in the cariogenicity of Streptococcus mutans.

Microbiology and immunology - 1 Jan 2003

Matsumura Mieko, Izumi Tomohiro, Matsumoto Michiyo, Tsuji Masato, Fujiwara Taku, Ooshima Takashi

Abstract excerpt

Streptococcus mutans produces glucan-binding proteins (Gbps), which appear to contribute to the virulence of S. mutans. GbpA and GbpC genes were inactivated by the insertion of antibiotic-resistant genes into each gbp gene of S. mutans MT8148 to generate Gbp-defective mutants. Sucrose dependent adherences of the GbpA- and GbpC-defective mutants were found to be significantly lower than those of their parent...

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Identifiers

PMID: 12725291
DOI: 10.1111/j.1348-0421.2003.tb03389.x

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