Article
Inhibition of CD10/neutral endopeptidase 24.11 promotes B-cell reconstitution and maturation in vivo.
Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 1993
Salles G, Rodewald H R, Chin B S, Reinherz E L, Shipp M A
Abstract excerpt
The common acute lymphoblastic leukemia antigen [(CALLA) CD10, neutral endopeptidase 24.11 (NEP)] is a cell-surface zinc metalloprotease expressed by a subpopulation of early murine B-lymphoid progenitors and by bone marrow stromal cells that support the earliest stages of B lymphopoiesis. In previous in vitro studies in which uncommitted murine hematopoietic progenitors plated on a stromal cell layer...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.