Article
Acute graft-versus-host-like disease induced by transplantation of human activated natural killer cells into SCID mice.
Transplantation - 1 Aug 1993
Xun C, Brown S A, Jennings C D, Henslee-Downey P J, Thompson J S
Abstract excerpt
Whereas T lymphocytes are essential for the initiation of acute graft-versus-host disease (aGVHD), it is not at all clear whether they or other cells or noncellular factors actually mediate the characteristic lesions. This report describes the in vivo effects of human NK cells, T cells, and cytokines on the induction of aGVHD in 4 Gy sublethally irradiated C.B-17 scid/scid (SCID) mice. Human NK and T lymphocytes...
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