Article
Elevated serum interleukin (IL)-12p40 levels in common variable immunodeficiency disease and decreased peripheral blood dendritic cells: analysis of IL-12p40 and interferon-gamma gene.
Clinical and experimental immunology - 1 May 2006
Martinez-Pomar N, Raga S, Ferrer J, Pons J, Munoz-Saa I, Julia M-R, de Gracia J, Matamoros N
Abstract excerpt
Common variable immunodeficiency disease (CVID) is a heterogeneous syndrome characterized by low immunoglobulin serum levels and recurrent bacterial infections. Several studies suggest that CVID patients have a polarized immune response towards a T helper type 1 phenotype (TH1). However, the factors causing the TH1 polarization remain to be determined in this disease. In the present study, serum interleukin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.