Article

Sfp1 regulates the SAGA component Tra1 in response to proteotoxic stress in <i>Saccharomyces cerevisiae</i>

2018-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Proteotoxic stress triggers transcriptional responses that allow cells to compensate for the accumulation of toxic misfolded proteins. Chromatin remodeling regulates gene expression in response to the accumulation of misfolded polyQ proteins associated with Huntington’s disease (HD). Tra1 is an essential component of both the SAGA/SLIK and NuA4 transcription co-activator complexes and is linked...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 80e17882-94dd-58f4-8b69-115159fa13bd
DOI: 10.1101/384602

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sfp1 regulates the SAGA component Tra1 in response to proteotoxic stress in <i>Saccharomyces cerevisiae</i>DOI 10.1101/384602Read

Transcriptional responses to proteotoxic stressors are profoundly diverse and tissue-specificSemantic proximity Read

Tra1 controls the transcriptional landscape of the aging cell.Semantic proximity Read

Ssd1 is required for thermotolerance and Hsp104-mediated protein disaggregation in Saccharomyces cerevisiae.Semantic proximity Read

Heat shock response relieves ER stress.Semantic proximity Read

Genetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1.Semantic proximity Read

Modular Architecture of the SAGA Complex Governs Stress Adaptation, Morphogenesis, and Histone Acetylation in <i>Candida albicans</i>Semantic proximity Read

Potential roles for mitochondria-to-HSF1 signaling in health and diseaseSemantic proximity Read

Loss of Hsp70-Hsp40 chaperone activity causes abnormal nuclear distribution and aberrant microtubule formation in M-phase of Saccharomyces cerevisiae.Semantic proximity Read

SAHA increases chaperone expression and reduces Z-alpha-1-antitrypsin polymers in a patient specific iPSC-based liver model for alpha-1-antitrypsin deficiencySemantic proximity Read

Redox regulation of yeast Hsp70 modulates protein quality control while directly triggering an Hsf1-dependent cytoprotective responseSemantic proximity Read

The Paf1 complex subunit Rtf1 buffers cells against the toxic effects of [PSI+] and defects in Rkr1-dependent protein quality control in Saccharomyces cerevisiae.Semantic proximity Read

The absence of specific yeast heat-shock proteins leads to abnormal aggregation and compromised autophagic clearance of mutant Huntingtin proteins.Semantic proximity Read