Article
Efficient translation of an SSA1-derived heat-shock mRNA in yeast cells limited for cap-binding protein and eIF-4F.
Molecular & general genetics : MGG - 10 Mar 1995
Barnes C A, MacKenzie M M, Johnston G C, Singer R A
Abstract excerpt
Eukaryotic mRNA molecules have a 5' cap structure that is recognized by the cap-binding component of translation initiation factor eIF-4F during protein synthesis. In the budding yeast Saccharomyces cerevisiae this cap-binding protein is encoded by the CDC33 gene. We report here that decreased gl...
Topics
- Eukaryotic Initiation Factor-4F
- Gene Expression Regulation, Fungal
- HSP70 Heat-Shock Proteins
- Mutation
- Peptide Chain Initiation, Translational
- Peptide Initiation Factors
- Polyribosomes
- RNA Cap-Binding Proteins
- RNA Caps
- RNA, Fungal
- RNA, Messenger