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Comparative evaluation of therapeutic DNA vaccines againstTrypanosoma cruziin mice

24 May 2007

Abstract excerpt

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major public health problem in most of Latin America. A key priority is the development of new treatments, due to the poor efficacy of current ones. We report here the comparative evaluation of therapeutic DNA vaccines encoding various T. cruzi antigens. ICR mice infected with 500 parasites intraperitoneally were treated at 5 and 12 days...

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PMID: 17521394
DOI: 10.1111/j.1574-695x.2007.00251.x

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