Article
T Cell Specificity: A Great Challenge in Chagas Disease
29 Jun 2021
Abstract excerpt
The CD4+and CD8+T cell immune response againstT. cruzi, the parasite causing Chagas disease, are relevant for both parasite control and disease pathogenesis. Several studies have been focused on their phenotype and functionally, but only a few have drilled down to identify the parasite proteins that are processed and presented to these cells, especially to CD4+T lymphocytes. Although approximately 10,000 proteins...
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