Article
Disruption of the actin cytoskeleton in yeast capping protein mutants.
Nature - 22 Mar 1990
Amatruda J F, Cannon J F, Tatchell K, Hug C, Cooper J A
Abstract excerpt
Capping protein controls the addition of actin subunits to the barbed end of actin filaments and nucleates actin polymerization in vitro. Capping protein has been identified in all eukaryotic cells examined so far; it is a heterodimer with subunits of relative molecular masses 32,000-36,000 (alpha-subunit) and 28,000-32,000 (beta-subunit). In skeletal muscle, capping protein (CapZ) probably binds the barbed ends...
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