Article
Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae.
The Journal of cell biology - 1 Aug 1993
Holtzman D A, Yang S, Drubin D G
Abstract excerpt
Abplp is a yeast cortical actin-binding protein that contains an SH3 domain similar to those found in signal transduction proteins that function at the membrane/cytoskeleton interface. Although no detectable phenotypes are associated with a disruption allele of ABP1, mutations that create a requi...
Topics
- Amino Acid Sequence
- Carrier Proteins
- Cytoskeletal Proteins
- Cytoskeleton
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Microfilament Proteins
- Molecular Sequence Data
- Morphogenesis
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Analysis