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Article

Gene manipulation by protoplast fusion and penicillin production by Penicillium chrysogenum.

Applied biochemistry and biotechnology - 1 Jan 1993

Tahoun M K

Abstract excerpt

Hybrids have been obtained by protoplast fusion of nitrate-nonutilizing cnx- and acetate-nonutilizing fac- mutants of Penicillium chrysogenum strains 4/95 and 26/818, respectively. Induced haplodization of the hybrids allowed the recovery of stable segregants, which were screened for penicillin production. The penicillin-producing segregants showed a wide range of titers that reached for a certain mutant to...

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PMID: 8323265
DOI: 10.1007/BF02919009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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