Article
Gene manipulation by protoplast fusion and penicillin production by Penicillium chrysogenum.
Applied biochemistry and biotechnology - 1 Jan 1993
Tahoun M K
Abstract excerpt
Hybrids have been obtained by protoplast fusion of nitrate-nonutilizing cnx- and acetate-nonutilizing fac- mutants of Penicillium chrysogenum strains 4/95 and 26/818, respectively. Induced haplodization of the hybrids allowed the recovery of stable segregants, which were screened for penicillin p...
Topics
- Chlorates
- Fluoroacetates
- Mutation
- Penicillins
- Penicillium chrysogenum
- Protoplasts
