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Article

The optimization of penicillin biosynthesis in fungi.

Trends in biotechnology - 1 Nov 1998

Peñalva M A, Rowlands R T, Turner G

Abstract excerpt

Penicillin production by Penicillium chrysogenum is not only commercially important but arguably the most intensively investigated secondary-metabolic pathway in fungi. Isolation of the structural genes encoding the three main penicillin-biosynthetic enzymes has stimulated the use of molecular approaches to optimize yield and permitted genetic analysis of current production strains, which are themselves the...

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PMID: 9830157
DOI: 10.1016/s0167-7799(98)01229-3

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