Article
Cancer cell societies and tumor progression
1 Jan 1993
Abstract excerpt
It is now well accepted that cancers are heterogeneous and contain multiple subpopulations of cancer cells that differ in important behavioral properties, such as growth rate, ability to metastasize and sensitivity to treatment. This review describes results using a mouse mammary tumor system to model the effect of heterogeneity on tumor growth and response to chemotherapy. Tumor subpopulations that differ in...
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