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Article

Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach

20 Feb 2015

Abstract excerpt

BACKGROUND: An essential question in cancer is why individuals with the same disease have different clinical outcomes. Progress toward a more personalized medicine in cancer patients requires taking into account the underlying heterogeneity at different molecular levels. RESULTS: Here, we present a model in which there are complex interactions at different cellular and systemic levels that account for the...

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PMID: 25853295
DOI: 10.1186/s13059-015-0599-z

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