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Article

Energy coupling between DNA binding and subunit association is responsible for the specificity of DNA-Arc interaction.

Protein science : a publication of the Protein Society - 1 Jun 1993

Silva J L, Silveira C F

Abstract excerpt

The effects of several DNA molecules on the free energy of subunit association of Arc repressor were measured. The association studies under equilibrium conditions were performed by the dissociating perturbation of hydrostatic pressure. The magnitude of stabilization of the subunit interaction was determined by the specificity of the protein-DNA interaction. Operator DNA stabilized the free energy of association...

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Identifiers

PMID: 8318899
DOI: 10.1002/pro.5560020608
PMCID: PMC2142413

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Source receipt: pubmed, retrieved 7 Sept 2026.

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