Article
Energy coupling between DNA binding and subunit association is responsible for the specificity of DNA-Arc interaction.
Protein science : a publication of the Protein Society - 1 Jun 1993
Silva J L, Silveira C F
Abstract excerpt
The effects of several DNA molecules on the free energy of subunit association of Arc repressor were measured. The association studies under equilibrium conditions were performed by the dissociating perturbation of hydrostatic pressure. The magnitude of stabilization of the subunit interaction wa...
Topics
- Bacteriophage P22
- Base Sequence
- DNA, Viral
- DNA-Binding Proteins
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Repressor Proteins
- Thermodynamics
- Viral Proteins
- Viral Regulatory and Accessory Proteins