Article
Effectiveness of Φ-value analysis in the binding process of Arc repressor dimer.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Jul 2011
Guo Xinlu, Zhang Jian, Chang Le, Wang Jun, Wang Wei
Abstract excerpt
Φ-value analysis has proved to be a powerful technique in protein folding studies. It has been used to study the transition state structures, to infer microscopic folding pathways, and to identify key residues in the protein folding process. However, its effectiveness in protein binding reaction has not been tested, especially when a fly-casting mechanism is involved. In this article we attempt to answer this...
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