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Article

[The causes of instability of artificial mini-chromosomes in yeasts mutant for chl genes].

Molekuliarnaia biologiia - 1 Jan 2000

Kuprina N Iu, Nikolaĭshvili N T, Pashina O B, Tsuladze A M, Larionov V L

Abstract excerpt

In mutants chl2, chl3, chl5, and chl6, which control mitotic chromosome transmission, the behaviour of the centromeric plasmids with various genes was analyzed. The main cause of chromosome instability in chl2, chl5, and chl6 is chromosome loss during cell division (1:0 segregation). The main cause of chromosome instability in chl3. is nondisjunction (2:0 segregation). According to this, the chl3 mutant, but not...

Topics

Chromosome Deletion
Chromosomes, Fungal
Genes, Fungal
Genetic Markers
Mutation
Plasmids
Ploidies
Saccharomyces cerevisiae
Transformation, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 3054502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3054502-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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