Article
Zidovudine resistance, syncytium-inducing phenotype, and HIV disease progression in a case-control study. The VA Cooperative Study Group.
Journal of acquired immune deficiency syndromes - 1 Aug 1993
St Clair M H, Hartigan P M, Andrews J C, Vavro C L, Simberkoff M S, Hamilton J D
Abstract excerpt
A case-control study of patients with progressive (cases) or nonprogressive (controls) disease was designed to determine the association among disease progression, zidovudine sensitivity, and syncytium-inducing phenotype. Viral isolates were screened for sensitivity to zidovudine using a peripheral blood mononuclear cell-based assay and for syncytium-inducing (SI) phenotype in MT2 cell culture. Thirty-four...
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