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Article

Viral phenotype and genotype as markers in clinical trials.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 1 Jan 1995

Katzenstein D A

Abstract excerpt

Treatment of AIDS and HIV infection is increasingly dependent on the use of surrogate markers to assess the efficacy of drug and biologic therapies in individual patients and in the clinical trials. Recent developments in laboratory techniques have resulted in new assays to measure circulating viral RNA in HIV-infected individuals, standardized methods to assess genotypic changes in virus associated with drug...

Topics

Antiviral Agents
Biomarkers
CD4 Lymphocyte Count
Clinical Trials as Topic
DNA, Viral
Disease Progression
Drug Resistance, Microbial
Genotype
Giant Cells
HIV
HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Phenotype

RNA, Viral

Source

Identifiers

PMID: 7552510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7552510-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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