Article
Differential expression of the human mucin genes MUC1 to MUC5 in relation to growth and differentiation of different mucus-secreting HT-29 cell subpopulations.
Journal of cell science - 1 Nov 1993
Lesuffleur T, Porchet N, Aubert J P, Swallow D, Gum J R, Kim Y S, Real F X, Zweibaum A
Abstract excerpt
Mucin expression was analysed, in relation to cell growth, in parental HT-29 cells and in two populations of mucus-secreting HT-29 cells selected by adaptation to methotrexate (HT29-MTX) or 5-fluorouracil (HT29-FU). These two populations express mature mucins that differ in their immunoreactivity...
Topics
- Blotting, Northern
- Cell Differentiation
- Cell Division
- Cell Line
- Fluorescent Antibody Technique
- Fluorouracil
- Gene Expression Regulation
- Humans
- Methotrexate
- Mucins
- Mucus
- Phenotype
- RNA, Messenger