Article
Specific secretion of gel-forming mucins and TFF peptides in HT-29 cells of mucin-secreting phenotype.
Biochimica et biophysica acta - 28 May 2001
Gouyer V, Wiede A, Buisine M P, Dekeyser S, Moreau O, Lesuffleur T, Hoffmann W, Huet G
Abstract excerpt
Trefoil factor family (TFF) peptides are typical secretory products of mucin-producing cells, e.g. of the gastrointestinal tract. Here, the expression and secretion of mucins and TFF peptides was studied in the HT-29 cell line throughout cellular growth and differentiation in relation to a mucin-secreting (HT-29 MTX) or an enterocyte-like (HT-29 G(-)) phenotype. mRNAs of several MUC and TFF genes were expressed...
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