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Article

Rapid, flow cytometric assay for NK alloreactivity reveals exceptions to rules governing alloreactivity.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Feb 2010

De Santis Dianne, Foley Bree A, John Elisabeth, Senitzer David, Christiansen Frank T, Witt Campbell S

Abstract excerpt

Alloreactive NK cells lyse target cells lacking self-HLA-C or the HLA-B-Bw4 epitope. Prior to haploidentical stem cell transplants, donor alloreactivity toward the patient is evaluated by natural killer (NK) cloning followed by testing of the clones in the (51)Cr-release assay. As only a few percent of NK clones are alloreactive, a large number of NK clones must be established and evaluated. This approach is...

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Identifiers

PMID: 19879950
DOI: 10.1016/j.bbmt.2009.10.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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