Heat-treated osteoblastic cell (ROS17/2.8)-conditioned medium induces the formation of osteoclast-like cells.

doi:10.1016/s0169-6009(08)80048-7

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Article

Heat-treated osteoblastic cell (ROS17/2.8)-conditioned medium induces the formation of osteoclast-like cells.

Bone and mineral - 1 Nov 1993

Kukita A, Kukita T, Hata K, Kurisu K, Kohashi O

Abstract excerpt

To study the effects of osteoblast products on osteoclast formation, we added the conditioned medium (CM) of rat osteoblastic cell line ROS17/2.8 to rat bone marrow cultures, in which tartrate-resistant acid phosphatase (TRAP)-positive osteoclast-like multinucleate cells (MNCs) formed in the pres...

Topics

Acid Phosphatase
Animals
Bone Marrow
Bone Marrow Cells
Bone Neoplasms
Bone Resorption
Calcitonin
Calcitriol
Cell Differentiation
Cell Movement
Cells, Cultured
Culture Media, Conditioned

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Dentin

Hot Temperature

Male

Osteoblasts

Osteoclasts

Osteosarcoma

Source

Open in PubMed

Identifiers

PMID: 8305877
DOI: 10.1016/s0169-6009(08)80048-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8305877-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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