Conditionally immortalized murine bone marrow stromal cells mediate parathyroid hormone-dependent osteoclastogenesis in vitro.

doi:10.1210/endo.139.4.5895

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Article

Conditionally immortalized murine bone marrow stromal cells mediate parathyroid hormone-dependent osteoclastogenesis in vitro.

Endocrinology - 1 Apr 1998

Liu B Y, Guo J, Lanske B, Divieti P, Kronenberg H M, Bringhurst F R

Abstract excerpt

PTH recruits and activates osteoclasts to cause bone resorption. These actions of PTH are thought to be mediated indirectly via type 1 PTH/PTH-related peptide receptors (PTH1Rs) expressed by adjacent marrow stromal or osteoblastic cells, although some evidence suggests that PTH may act directly o...

Topics

Acid Phosphatase
Animals
Antigens, Polyomavirus Transforming
Bone Marrow Cells
Calcitonin
Calcitriol
Cell Line, Transformed
Coculture Techniques
Hot Temperature
Humans
Mice
Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Osteoclasts

Parathyroid Hormone

Rats

Receptors, Parathyroid Hormone

Spleen

Source

Open in PubMed

Identifiers

PMID: 9528982
DOI: 10.1210/endo.139.4.5895

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9528982-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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