Polymorphism at codon 36 of the p53 gene.

Article

Polymorphism at codon 36 of the p53 gene.

Oncogene - 1 Jan 1994

Felix C A, Brown D L, Mitsudomi T, Ikagaki N, Wong A, Wasserman R, Womer R B, Biegel J A

Abstract excerpt

A polymorphism at codon 36 in exon 4 of the p53 gene was identified by single strand conformation polymorphism (SSCP) analysis and direct sequencing of genomic DNA PCR products. The polymorphic allele, present in the heterozygous state in genomic DNAs of four of 100 individuals (4%), changes the...

Topics

Base Sequence
Codon
Genes, p53
Humans
Molecular Sequence Data
Mutation
Polymorphism, Genetic

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