Article
Effects on virulence of mutations in a locus essential for hyaluronic acid capsule expression in group A streptococci.
Infection and immunity - 1 Feb 1994
Wessels M R, Goldberg J B, Moses A E, DiCesare T J
Abstract excerpt
Mucoid or highly encapsulated strains of group A streptococci have been associated both with unusually severe infections and with acute rheumatic fever. Previously, we described an acapsular mutant, TX4, derived from a mucoid M-type 18 strain of a group A streptococcus by transposon mutagenesis (M. R. Wessels, A. E. Moses, J. B. Goldberg, and T. J. DiCesare, Proc. Natl. Acad. Sci. USA 88:8317-8321, 1991). We now...
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