Article
Mutual Exclusivity of Hyaluronan and Hyaluronidase in Invasive Group A Streptococcus
30 Sept 2014
Abstract excerpt
A recent analysis of group A Streptococcus (GAS) invasive infections in Australia has shown a predominance of M4 GAS, a serotype recently reported to lack the antiphagocytic hyaluronic acid (HA) capsule. Here, we use molecular genetics and bioinformatics techniques to characterize 17 clinical M4 isolates associated with invasive disease in children during this recent epidemiology. All M4 isolates lacked HA...
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