Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Disease Isolates of Serotype M4 and M22 Group A Streptococcus Lack Genes Required for Hyaluronic Acid Capsule Biosynthesis

7 Nov 2012

Abstract excerpt

UNLABELLED: Group A streptococcus (GAS) causes human pharyngitis and invasive infections and frequently colonizes individuals asymptomatically. Many lines of evidence generated over decades have shown that the hyaluronic acid capsule is a major virulence factor contributing to these infections. While conducting a whole-genome analysis of the in vivo molecular genetic changes that occur in GAS during longitudinal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Pneumonia and Respiratory Infections
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23131832
DOI: 10.1128/mbio.00413-12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Disease Isolates of Serotype M4 and M22 Group A Streptococcus Lack Genes Required for Hyaluronic Acid Capsule BiosynthesisPMID 23131832Read ↗

Mutual Exclusivity of Hyaluronan and Hyaluronidase in Invasive Group A StreptococcusSemantic proximity Read ↗

Asymptomatic carriage of group A streptococcus is associated with elimination of capsule production.Semantic proximity Read ↗

Molecular and genomic characterization of pathogenic traits of group A Streptococcus pyogenesSemantic proximity Read ↗

Capsular Polysaccharide of Group A StreptococcusSemantic proximity Read ↗

Transcription of the Streptococcus pyogenes hyaluronic acid capsule biosynthesis operon is regulated by previously unknown upstream elements.Semantic proximity Read ↗

A Controlled Human Infection Model of Group A Streptococcus Pharyngitis: Which Strain and Why?Semantic proximity Read ↗

T4 Pili Promote Colonization and Immune Evasion Phenotypes of Nonencapsulated M4 Streptococcus pyogenes.Semantic proximity Read ↗

Streptococcus pyogenes genes that promote pharyngitis in primatesSemantic proximity Read ↗

New understanding of the group A Streptococcus pathogenesis cycle.Semantic proximity Read ↗

Hyaluronan Breakdown Contributes to Immune Defense against Group A StreptococcusSemantic proximity Read ↗

Contribution of Exogenous Genetic Elements to the Group A Streptococcus MetagenomeSemantic proximity Read ↗

Role of Hyaluronidase in Subcutaneous Spread and Growth of Group A StreptococcusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.