Article
Sequence analysis and functional studies of interleukin-3 receptor alpha subunit-encoding cDNAs amplified from KG-1 leukemic cells and normal human marrow.
Gene - 31 Dec 1993
Rapoport A P, DiPersio J F
Abstract excerpt
Two partial cDNAs encoding the human interleukin-3 receptor alpha subunit (IL-3R alpha) were cloned from KG-1 leukemic cells using the polymerase chain reaction. Sequence analysis of these cDNAs predicted two single-amino-acid (aa) changes as compared with the published TF-1 leukemic cell IL-3R a...
Topics
- Base Sequence
- Bone Marrow
- Bone Marrow Cells
- Cells, Cultured
- DNA, Complementary
- Humans
- Leukemia
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Receptors, Interleukin-3
- Tumor Cells, Cultured
