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Article

Pyrimidine biosynthesis genes (pyrE and pyrF) of an extreme thermophile, Thermus thermophilus.

Applied and environmental microbiology - 1 Jun 1996

Yamagishi A, Tanimoto T, Suzuki T, Oshima T

Abstract excerpt

We have isolated uracil auxotrophic mutants of an extreme thermophile, Thermus thermophilus. A part of the pyrimidine biosynthetic operon including genes for orotate phosphoribosyltransferase (pyrE) and for orotidine-5'-monophosphate decarboxylase (pyrF) was cloned and sequenced. The pyrE gene can be a bidirectional marker for the gene manipulation system of the thermophile.

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Source

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Identifiers

PMID: 8787418
DOI: 10.1128/aem.62.6.2191-2194.1996
PMCID: PMC167999

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