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Article

Alpha-1-proteinase inhibitor and pulmonary haemorrhage in systemic vasculitis.

Advances in experimental medicine and biology - 1 Jan 1993

O'Donoghue D J, Guickian M, Blundell G, Winney R J

Abstract excerpt

Alpha-1-proteinase inhibitor phenotypes and levels were examined in 40 antineutrophil cytoplasmic antibody positive cases of systemic vasculitis. An excess of PiZ and PiS alleles were associated with the development of pulmonary haemorrhage and alpha-1-proteinase inhibitor levels were lower in th...

Topics

Alleles
Antibodies, Antineutrophil Cytoplasmic
Autoantibodies
Hemorrhage
Humans
Immunoglobulin G
Lung Diseases
Myeloblastin
Peroxidase
Phenotype
Serine Endopeptidases
Vasculitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

alpha 1-Antitrypsin

Source

Identifiers

PMID: 8296629
DOI: 10.1007/978-1-4757-9182-2_54

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8296629-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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