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Article

Characterization of folding intermediates using prolyl isomerase.

Biochemistry - 25 Jan 1994

Veeraraghavan S, Nall B T

Abstract excerpt

Structure-reactivity relationships of human peptidyl prolyl cis-trans isomerase (PPI) toward the two slow folding reactions of yeast iso-2 cytochrome c have been used to characterize the structure of folding intermediates in the vicinity of critical prolines. We propose that the relative catalytic efficiency of PPI for the protein substrate relative to a peptide substrate, (kcat/Km)rel, is a measure of structure...

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Identifiers

PMID: 8292595
DOI: 10.1021/bi00169a009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of folding intermediates using prolyl isomerase.PMID 8292595Read ↗

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