Isolation of temperature sensitive mutants of Autographa californica nuclear polyhedrosis virus: phenotype characterization of baculovirus mutants defective in very late gene expression.

Abstract excerpt

Temperature sensitive mutants of Autographa californica nuclear polyhedrosis virus were isolated following exposure of parental replicating virus to 5-bromo-2'-deoxyuridine. Two mutants designated ts317 and ts538 were characterized in detail. Both mutants synthesized viral DNA but were defective in infectious extracellular virus production at the nonpermissive temperature suggesting defects in late gene...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blotting, Western
• Share to Cell Line