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Article

A mechanism for negative gene regulation in Autographa californica multinucleocapsid nuclear polyhedrosis virus.

Journal of virology - 1 Jul 1997

Leisy D J, Rasmussen C, Owusu E O, Rohrmann G F

Abstract excerpt

The Autographa californica multinucleocapsid nuclear polyhedrosis virus (AcMNPV) ie-1 gene product (IE-1) is thought to play a central role in stimulating early viral transcription. IE-1 has been demonstrated to activate several early viral gene promoters and to negatively regulate the promoters of two other AcMNPV regulatory genes, ie-0 and ie-2. Our results indicate that IE-1 negatively regulates the expression...

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Identifiers

PMID: 9188574
DOI: 10.1128/JVI.71.7.5088-5094.1997
PMCID: PMC191742

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