Disulfide bridges are not involved in penicillin-binding protein 1b dimerization in Escherichia coli.

Abstract excerpt

PBP1b can be found as a dimer in Escherichia coli. Previous results suggested that dimerization involved the cysteine(s) in an intermolecular disulfide bond. We show that either deletion mutants or a mutant without cysteines is fully active and still binds penicillin and that the latter can also form dimers.

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