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Article

Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens.

The Journal of biological chemistry - 28 Jan 2005

Lucet Isabelle S, Tynan Fleur E, Adams Vicki, Rossjohn Jamie, Lyras Dena, Rood Julian I

Abstract excerpt

Members of the large serine resolvase family of site-specific recombinases are responsible for the movement of several mobile genetic elements; however, little is known regarding the structure or function of these proteins. TnpX is a serine recombinase that is responsible for the movement of the chloramphenicol resistance elements of the Tn4451/3 family. We have shown that TnpX binds differentially to its...

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PMID: 15542858
DOI: 10.1074/jbc.M409702200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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