Article
Relative roles of osteoclast colony-stimulating factor and macrophage colony-stimulating factor in the course of osteoclast development.
Experimental hematology - 1 Jan 1994
Lee T H, Fevold K L, Muguruma Y, Lottsfeldt J L, Lee M Y
Abstract excerpt
Although recent studies have shown that osteopetrotic (op/op) mice lack macrophage colony-stimulating factor (M-CSF or CSF-1), the precise role of M-CSF in the development of immature osteoclasts remains unknown. Using a recently discovered osteoclast-specific colony-stimulating factor (O-CSF) an...
Topics
- Animals
- Bone Marrow
- Bone Marrow Cells
- Calcitriol
- Cell Adhesion
- Cell Differentiation
- Cell Division
- Cell Survival
- Cells, Cultured
- Colony-Stimulating Factors
- Culture Media, Conditioned
- Female
- Lymphoid Tissue
- Macrophage Colony-Stimulating Factor
- Male
- Mice
- Mice, Mutant Strains
- Osteoclasts