Article
The role of growth regulatory aberrations in progression of human colon carcinoma.
Cancer metastasis reviews - 1 Sept 1993
Howell G M, Sun L, Ziober B L, Wu S P, Brattain M G
Abstract excerpt
Colon carcinoma is a multistage disease. Most malignancies arise from pre-existing benign tumors. Multiple chromosomal defects affecting oncogene and tumor suppressor gene function are associated with disease progression. These aberrations result in an imbalance between the normal positive and ne...
Topics
- Animals
- Base Sequence
- Cell Division
- Colonic Neoplasms
- Humans
- Models, Biological
- Molecular Sequence Data
- Neoplasm Staging
- Phenotype
- Transplantation, Heterologous
- Tumor Cells, Cultured