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Article

Trophic actions of ciliary neurotrophic factor on murine embryonic carcinoma cells.

The European journal of neuroscience - 1 Aug 1993

Gupta S K, Haggarty A J, Carbonetto S, Riopelle R J, Richardson P M, Dunn R J

Abstract excerpt

Recombinant rat CNTF (ciliary neurotrophic factor) at picomolar concentration prevents the death of P19 murine embryonic carcinoma cells that usually follows upon withdrawal of serum from the culture medium. For prolonged survival of P19 cells in serum-free medium, insulin must also be present. In the presence or absence of serum, CNTF stimulates the differentiation of P19 cells, inducing the formation of...

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Source

Identifiers

PMID: 8281314
DOI: 10.1111/j.1460-9568.1993.tb00949.x

Genes

CNTF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Trophic actions of ciliary neurotrophic factor on murine embryonic carcinoma cells.PMID 8281314Read ↗

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The Neurotrophins and Neuropoietic Cytokines: Two Families of Growth Factors Acting on Neural and Hematopoietic CellsSemantic proximity Read ↗

Structure-function studies of nerve growth factor: functional importance of highly conserved amino acid residues.Semantic proximity Read ↗

Growth hormone and insulin-like growth factor-I: effects on the growth of glioma cell lines.Semantic proximity Read ↗

Fibroblast growth factor differentially modulates the neurotransmitter phenotype of cultured sympathetic neurons.Semantic proximity Read ↗

Collaborative and reciprocal effects of ciliary neurotrophic factor and nerve growth factor on the neuronal phenotype of human neuroblastoma cells.Semantic proximity Read ↗

Investigation of possible autocrine functions for rat GRO/CINC (cytokine-induced neutrophil chemoattractant).Semantic proximity Read ↗

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells.Semantic proximity Read ↗

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