Article
Trophic actions of ciliary neurotrophic factor on murine embryonic carcinoma cells.
The European journal of neuroscience - 1 Aug 1993
Gupta S K, Haggarty A J, Carbonetto S, Riopelle R J, Richardson P M, Dunn R J
Abstract excerpt
Recombinant rat CNTF (ciliary neurotrophic factor) at picomolar concentration prevents the death of P19 murine embryonic carcinoma cells that usually follows upon withdrawal of serum from the culture medium. For prolonged survival of P19 cells in serum-free medium, insulin must also be present. I...
Topics
- Animals
- Carcinoma
- Cell Differentiation
- Cell Survival
- Ciliary Neurotrophic Factor
- Mice
- Neoplasms, Germ Cell and Embryonal
- Nerve Growth Factors
- Nerve Tissue Proteins
- Neurons
- Phenotype
- Receptor, Ciliary Neurotrophic Factor
