Collaborative and reciprocal effects of ciliary neurotrophic factor and nerve growth factor on the neuronal phenotype of human neuroblastoma cells.

doi:10.1046/j.1471-4159.1998.70041411.x

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Article

Collaborative and reciprocal effects of ciliary neurotrophic factor and nerve growth factor on the neuronal phenotype of human neuroblastoma cells.

Journal of neurochemistry - 1 Apr 1998

Zinman L H, Lawrance G, Wang W, Verge V M, Dow K E, Maurice D H, Richardson P M, Riopelle R J

Abstract excerpt

We have probed the molecular basis of functional effects of ciliary neurotrophic factor (CNTF) and nerve growth factor (NGF) on aspects of the neuronal differentiation of LA-N-2 neuroblastoma cells. The influence of CNTF on the cholinergic phenotype can be accounted for by transcriptional/transla...

Topics

Cell Adhesion
Choline O-Acetyltransferase
Ciliary Neurotrophic Factor
Humans
In Situ Hybridization
Nerve Growth Factors
Nerve Tissue Proteins
Neuroblastoma
Neurons
Phenotype
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Receptor, Nerve Growth Factor

Receptor, trkA

Receptors, Nerve Growth Factor

Transcription, Genetic

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 9523557
DOI: 10.1046/j.1471-4159.1998.70041411.x

Genes

CNTF
NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9523557-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Collaborative and reciprocal effects of ciliary neurotrophic factor and nerve growth factor on the neuronal phenotype of human neuroblastoma cells.PMID 9523557Read ↗

Differentiation of cholinergic neurons and physiological role of ciliary neurotrophic factor (CNTF).Semantic proximity Read ↗

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BDNF and CNTF regulate cholinergic properties of sympathetic neurons through independent mechanisms.Semantic proximity Read ↗

Agonistic and antagonistic variants of ciliary neurotrophic factor (CNTF) reveal functional differences between membrane-bound and soluble CNTF alpha-receptor.Semantic proximity Read ↗

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