Maximum-likelihood estimation of phylogeny from DNA sequences when substitution rates differ over sites.

doi:10.1093/oxfordjournals.molbev.a040082

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Article

Maximum-likelihood estimation of phylogeny from DNA sequences when substitution rates differ over sites.

Molecular biology and evolution - 1 Nov 1993

Yang Z

Abstract excerpt

Felsenstein's maximum-likelihood approach for inferring phylogeny from DNA sequences assumes that the rate of nucleotide substitution is constant over different nucleotide sites. This assumption is sometimes unrealistic, as has been revealed by analysis of real sequence data. In the present paper...

Topics

Animals
Artiodactyla
DNA
Genetic Variation
Lagomorpha
Mathematics
Models, Genetic
Models, Statistical
Phylogeny
Primates
Probability
Rodentia
Software

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