Article
A likelihood framework to analyse phyletic patterns.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Dec 2008
Cohen Ofir, Rubinstein Nimrod D, Stern Adi, Gophna Uri, Pupko Tal
Abstract excerpt
Probabilistic evolutionary models revolutionized our capability to extract biological insights from sequence data. While these models accurately describe the stochastic processes of site-specific substitutions, single-base substitutions represent only a fraction of all the events that shape genomes. Specifically, in microbes, events in which entire genes are gained (e.g. via horizontal gene transfer) and lost...
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