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Article

Identifying site-specific substitution rates.

Molecular biology and evolution - 1 Feb 2003

Meyer Sonja, von Haeseler Arndt

Abstract excerpt

A maximum likelihood framework for estimating site-specific substitution rates is presented that does not require any prior assumptions about the rate distribution. We show that, when the branching pattern of the underlying tree is known, the analysis of pairs of positions is sufficient to estimate site-specific rates. In the abscense of a known topology, we introduce an iterative procedure to estimate...

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PMID: 12598684
DOI: 10.1093/molbev/msg019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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